{"id":14863,"date":"2017-05-11T15:58:13","date_gmt":"2017-05-11T12:58:13","guid":{"rendered":"http:\/\/www.fhcam.net\/?p=14863"},"modified":"2017-05-11T15:58:13","modified_gmt":"2017-05-11T12:58:13","slug":"kimyasal-maruziyetin-biyolojik-olarak-izlenmesi-icin-yapilmasi-gereken-tetkikler","status":"publish","type":"post","link":"https:\/\/saglikdanisma.net\/is\/kimyasal-maruziyetin-biyolojik-olarak-izlenmesi-icin-yapilmasi-gereken-tetkikler\/","title":{"rendered":"Kimyasal Maruziyet in Biyolojik olarak \u0130zlenmesi i\u00e7in Yap\u0131lmas\u0131 Gereken Tetkikler"},"content":{"rendered":"

Kimyasallarla \u00e7al\u0131\u015fanlarda kimyasal\u00a0maruziyet i\u00a0tespit etmek i\u00e7in ki\u015fisel\u00a0\u00f6l\u00e7\u00fcmleri yap\u0131labilir. Bunun i\u00e7in \u00f6ncelikle u\u011fra\u015f\u0131lan\/kullan\u0131lan kimyasal maddenin MSDS’i kontrol edilerek madde i\u00e7eri\u011fi tespit edilir ve bu maddelere g\u00f6re kanda veya idrarda a\u015fa\u011f\u0131daki \u00f6l\u00e7\u00fcmler yapt\u0131r\u0131larak \u00e7al\u0131\u015fan\u0131n ki\u015fisel maruziyeti ortaya konabilir.<\/p>\n

\u0130norganik ve Organik Metal Maddeler:<\/h2>\n

Al\u00fcminyum:<\/strong> Al\u00fcminyum Serum < 1 \u03bcg\/100 ml; Al\u00fcminyum \u0130drar < 50 \u03bcg\/g kreatinin<\/p>\n

Antimon:<\/strong> Antimon \u0130drar < 1 \u03bcg\/g kreatinin<\/p>\n

Arsenik:<\/strong> Total arsenik \u0130drar < 40 \u03bcg\/g kreatinin<\/p>\n

Azot oksit:<\/strong> N2O \u0130drar 60 \u03bcg\/g kreatinin<\/p>\n

Bak\u0131r:<\/strong> Bak\u0131r \u0130drar < 50 \u03bcg\/g kreatinin; Bak\u0131r Serum < 0.14 mg\/100 ml<\/p>\n

Baryum:<\/strong> Baryum \u0130drar < 15 \u03bcg\/g kreatinin; Baryum Kan < 0.8 \u03bcg\/100 ml<\/p>\n

Berilyum:<\/strong> Berilyum \u0130drar < 2 \u03bcg\/g kreatinin<\/p>\n

Civa (inorganik):<\/strong> Civa \u0130drar < 5 \u03bcg\/g kreatinin; Civa Kan < 1 \u03bcg\/100 ml<\/p>\n

Metilc\u0131va:<\/strong> Civa Kan < 1 \u03bcg\/100 ml<\/p>\n

\u00c7inko:<\/strong> \u00c7inko \u0130drar < 0.9 mg\/g kreatinin; \u00c7inko Serum < 170 \u03bcg\/100 ml<\/p>\n

Flor:<\/strong> Flor \u0130drar < 0.5 mg\/g kreatinin<\/p>\n

G\u00fcm\u00fc\u015f:<\/strong> G\u00fcm\u00fc\u015f \u0130drar < 1 \u03bcg\/g kreatinin; G\u00fcm\u00fc\u015f Serum < 0.5 \u03bcg\/100 ml<\/p>\n

Kadmiyum:<\/strong> Kadmiyum \u0130drar < 2 \u03bcg\/g kreatinin; Kadmiyum Kan < 0.5 \u03bcg\/100 ml 0.5 \u03bcg\/100 ml<\/p>\n

Krom VI (\u00c7\u00f6z\u00fcnen bile\u015fikleri):<\/strong> Krom \u0130drar < 1 \u03bcg\/g kreatinin<\/p>\n

Kobalt:<\/strong> Kobalt \u0130drar < 2 \u03bcg\/g kreatinin; Kobalt Kan < 0.2 \u03bcg\/100 ml; Kobalt Serum < 0.05 \u03bcg\/100 ml<\/p>\n

Kur\u015fun:<\/strong> Kur\u015fun Kan < 25 \u03bcg\/100 ml; Kur\u015fun \u0130drar < 50 \u03bcg\/g kreatinin; Kur\u015fun \u0130drar < 600 \u03bcg\/24 saat<\/p>\n

Manganez:<\/strong> Manganez \u0130drar < 3 \u03bcg\/g kreatinin; Manganez Kan < 1 \u03bcg\/100 ml<\/p>\n

Nikel (\u00e7\u00f6z\u00fcnen bile\u015fikler):<\/strong> Nikel \u0130drar < 2 \u03bcg\/g kreatinin<\/p>\n

Selenyum:<\/strong> Selenyum Serum < 15 \u03bcg\/100 ml; Selenyum \u0130drar < 25 \u03bcg\/g kreatinin<\/p>\n

\"\"<\/p>\n

 <\/p>\n

Organik Maddeler:<\/h2>\n

Alifatik and Alisiklik Hidrokarbonlar<\/h3>\n

n-Hekzan: 2-Hekzanol \u0130drar 0.2 \u03bcg\/g kreatinin; 2,5-Hekzanedion \u0130drar 2 mg\/g kreatinin \u0130lk \u00e7al\u0131\u015fma g\u00fcn\u00fcn\u00fcn
\nsonunda ve 4 mg\/g kreatinin \u00c7al\u0131\u015fma haftas\u0131n\u0131n sonunda<\/p>\n

Siklohekzan: siklohekzanol \u0130drar 3.2 mg\/g kreatinin<\/p>\n

Benzen: Fenol \u0130drar < 20 mg\/g kreatinin; Benzen Kan < 2 \u03bcg\/100 ml<\/p>\n

Toluen: Hippurik asit \u0130drar < 1.5 g\/g kreatinin; \u03bf-Kresol \u0130drar < 0.3 mg\/g kreatinin; Toluen Kan 0.05 mg\/100 ml<\/p>\n

Etil benzen: Mandelik asit \u0130drar 1 g\/g kreatinin; Etil benzen Kan 0.15 mg\/100 ml<\/p>\n

Stiren: Mandelik asit \u0130drar 800 mg\/g kreatinin; Fenil glioksilik asit \u0130drar 250 mg\/g kreatinin; Stiren Kan 0.1 mg\/100 ml<\/p>\n

Ksilen: Metil hippurik asit \u0130drar 1.5 g\/g kreatinin<\/p>\n

Polisiklik hidro karbonlar: 1-Hidroksipiren \u0130drar < 2 \u03bcg\/g kreatinin (< 1 \u03bcmol\/mol kreatinin)<\/p>\n

Halojenli Hidrokarbonlar:<\/h3>\n

Vinil klorid: Tiyodiglikolik asit \u0130drar < 2 mg\/g kreatinin<\/p>\n

Trikloroetilen: Trikloretanol \u0130drar 150 mg\/g kreatinin; Triklorasetikasit \u0130drar 75 mg\/g kreatinin<\/p>\n

Tetrakloretilen: Tetrakloretilen Kan 100 \u03bcg\/100 ml Etkilenmeden 16 saat sonra; Tetrakloretilen \u0130drar 70 \u03bcg\/g kreatinin Etkilenmeden 16 saat sonra<\/p>\n

Halotan: Trifloroasetik asit \u0130drar 10 mg\/g kreatinin<\/p>\n

Amino ve nitro t\u00fcrevleri<\/h3>\n

Trietilamin (TEA): TEA+TEA-azotoksit \u0130drar 60 mg\/g kreatinin E\u011fer (ortam \u00f6l\u00e7\u00fcm\u00fc) TWA: 2.5 ppm ise<\/p>\n

Dimetilamin (DMEA): DMEA+ DMEA-azotoksit \u0130drar 90 mg\/g kreatinin<\/p>\n

Anilin: \u03c1-aminofenol \u0130drar 30 mg\/g kreatinin; Methemoglobin Kan < % 2<\/p>\n

Alkoller<\/h3>\n

Metanol: Metanol \u0130drar < 2.5 mg\/g kreatinin; Formik asit \u0130drar < 60 mg\/g kreatinin<\/p>\n

Aseton: \u0130drar < 2 mg\/g kreatinin<\/p>\n

Glikoller<\/h3>\n

Etilen glikol: Okzalik asit \u0130drar < 50 mg\/g kreatinin<\/p>\n

Ketonlar<\/h3>\n

Aseton: Aseton \u0130drar < 2 mg\/g kreatinin; Aseton Kan < 0.2 mg\/100 ml<\/p>\n

Siklohekzanon: Siklohekzanol \u0130drar 20 mg\/g kreatinin<\/p>\n

Metiletilketon: Metiletilketon \u0130drar 2.5 mg\/g kreatinin<\/p>\n

Metil-n-butilketon: 2,5-Hekzanedion \u0130drar 4 mg\/g kreatinin \u00c7al\u0131\u015fma haftas\u0131 sonunda<\/p>\n

Metilizobutil keton: Metilizobutil keton \u0130drar 0.5 mg\/g kreatinin<\/p>\n

Di\u011ferleri:<\/h3>\n

Furfural Furoik asit \u0130drar < 65 mg\/g kreatinin<\/p>\n

Dimetilformamid: N-metilformamid \u0130drar 30 mg\/g kreatinin; Dimetilformamid Kan 0.15 mg\/100 ml; N-metilformamid Kan 0.1 mg\/100 ml; N-asetil-S-(N-metil karbamoyl) sistein \u0130drar 40 mg\/g kreatinin<\/p>\n

Akrilamid: S-(2-Karboksietil sistein \u0130drar ???<\/p>\n

Maleik anhidrit: Maleik asit \u0130drar < 1.5 mg\/g kreatinin<\/p>\n

Fenol: Fenol \u0130drar < 20 mg\/g kreatinin<\/p>\n

Bo\u011fucular (Asfiksiyanlar)<\/h3>\n

Karbonmonoksit: Karboksi hemoglobin Kan < % 1; Karbonmonoksit Kan < 0.15 ml\/100 ml<\/p>\n

Siyan\u00fcrler ve alifatik nitriller: Tiyosiyanat \u0130drar < 6 mg\/g kreatinin; Siyan\u00fcr Kan < 10 \u03bcg\/100 ml sigara i\u00e7iyorsa: < 50 \u03bcg\/100 ml<\/p>\n

\u00d6zel bile\u015fikler d\u0131\u015f\u0131nda Methemoglobin olu\u015fturan maddeler: Methemoglobin Kan < % 2<\/p>\n

Pestisitler:<\/h3>\n

Organofosforlar ve Karbamat insektisitler: Kolinesteraz Alyuvar % 30 inhibisyon; Kolinesteraz Plazma % 50 inhibisyon; Kolinesteraz Tam kan % 30 inhibisyon; Dialkilfosfataz \u0130drar ??<\/p>\n

Paration: p-Nitrofenol \u0130drar 0.5 mg\/g kreatinin<\/p>\n

Karbaril: 1-Naftol \u0130drar 10 mg\/g kreatinin<\/p>\n

DDT: DDT+DDE+DDD Kan < 10 \u03bcg\/100 ml<\/p>\n

Dieldrin: Dieldrin Kan < 1 \u03bcg\/100 ml<\/p>\n

Hekzaklorobenzen: Hekzaklorobenzen Kan < 0.3 \u03bcg\/100 ml<\/p>\n

Dinitroortokresol: Dinitroortokresol Kan 1mg\/100 ml<\/p>\n

Etilenoksit: Etilenoksit Kan 0.8 \u03bcg\/100 ml<\/p>\n

\u00c7SGB’n\u0131n \u0130SG\u0130P ait \u00c7al\u0131\u015fma Ya\u015fam\u0131nda Sa\u011fl\u0131k G\u00f6zetim Rehberinden al\u0131nt\u0131d\u0131r. Kimyasal maruziyet –<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Kimyasallarla \u00e7al\u0131\u015fanlarda kimyasal\u00a0maruziyet i\u00a0tespit etmek i\u00e7in ki\u015fisel\u00a0\u00f6l\u00e7\u00fcmleri yap\u0131labilir. Bunun i\u00e7in \u00f6ncelikle u\u011fra\u015f\u0131lan\/kullan\u0131lan kimyasal maddenin MSDS’i kontrol edilerek madde i\u00e7eri\u011fi tespit edilir ve bu maddelere g\u00f6re kanda veya idrarda a\u015fa\u011f\u0131daki \u00f6l\u00e7\u00fcmler yapt\u0131r\u0131larak \u00e7al\u0131\u015fan\u0131n ki\u015fisel maruziyeti ortaya konabilir. \u0130norganik ve Organik Metal Maddeler: Al\u00fcminyum: Al\u00fcminyum Serum < 1 \u03bcg\/100 ml; Al\u00fcminyum \u0130drar < 50 \u03bcg\/g kreatinin Antimon: […]<\/p>\n","protected":false},"author":4,"featured_media":14943,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[93],"tags":[341,342,343,344,318],"class_list":["post-14863","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-isyeri-hekimi-rehberi","tag-kimyasal","tag-kimyasal-etkilenme","tag-laboratuar","tag-referans-degerler","tag-rehber"],"_links":{"self":[{"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/posts\/14863","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/comments?post=14863"}],"version-history":[{"count":0,"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/posts\/14863\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/"}],"wp:attachment":[{"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/media?parent=14863"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/categories?post=14863"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saglikdanisma.net\/is\/wp-json\/wp\/v2\/tags?post=14863"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}